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Author

Cinya Chung

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Open access Sep 2026

A Common Small-Molecule Inhibitor Targeting Multiple Siglecs Associated with Immune Checkpoint Suppression of Cytotoxicity and Phagocytosis

A truncated glycolyl sialoside (R3) was found to strongly inhibit the interaction of Siglec-10 with HER2-low MCF-7 cells, substantially enhancing macrophage-mediated phagocytosis and cytotoxicity in cell-based assays.

Cinya Chung, Ruo-Fan Li, Li-Chun Cheng et al. · 0 citations

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