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Cícero Matheus Lima Amaral

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Open access Sep 2026

High-intensity interval training modulates APP expression and reduces neuronal apoptosis in a β-amyloid-induced model of Alzheimer’s disease: hippocampal evidence

High-intensity interval training (HIIT) has emerged as a promising non-pharmacological strategy for neuroprotection, although its molecular effects in Alzheimer’s disease (AD) remain unclear. This study investigated the effects of HIIT on gene expression (FNDC5, PPARGC1A, APP), protein expression, cognitive performance...

Welton Daniel Nogueira Godinho, Francisco Sérgio Lopes Vasconcelos, Cícero Matheus Lima Amaral et al. · 0 citations

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