Curcumin-Loaded Ligand-Conjugated Chitosan Nanoparticles: A Comparative Study of Folic Acid, Phenylalanine, and Butyric Acid Conjugates for Colorectal Cancer
Enhanced efficacy is attributed to the synergistic action of butyric acid as a histone deacetylase inhibitor (HDACi), which complements curcumin’s anticancer activity.