Open access
Aug 2026
Glioblastoma Invasion Remodels Neural Circuits and Drives Persistent GABAergic Dysfunction in Human Brain Organoids
This human iPSC-derived tumor–brain organoid platform provides a reliable and scalable system for studying complex tumor-neural interactions and exploring therapeutic approaches that aim to eliminate the tumor while preserving neural function.
Ewa Grassin, H. Chintalapudi, Xianjun Dong et al.
· bioRxiv · 0 citations