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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chunlai Chen

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Open access Sep 2026

Automated kinetic-scheme-free sorting of single-molecule fluorescence events using a deep learning based hidden-state method

Single-molecule fluorescence techniques have revolutionized our ability to probe biomolecular dynamics by resolving molecular heterogeneity and transient states inaccessible to ensemble measurements. However, conventional analysis pipelines remain constrained by several factors that compromise both reproducibility and...

Shu-Qi Zhou, Wen-Qi Zeng, Yuan Yao et al. · 0 citations
Jul 2026

A Glimpse into the Initial Microsecond of Biomolecular Condensation.

Investigating the first microsecond of peptide condensation through temperature jump infrared spectroscopy and molecular dynamics simulations reveals that hydrogen bonding could enable hydrophobic disordered proteins to adopt preorganized conformations in response to environmental stimuli and serve as a key factor in m...

Longchen Zhu, Guohong Liao, Yumeng Zhang et al. · 0 citations

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