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Chun-Zheng Wang

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Oct 2026

Alnustone ameliorates atopic dermatitis by rebalancing TAp63/ΔNp63 to upregulate filaggrin and restore skin barrier function.

Atopic dermatitis (AD) is a chronic, pruritic, erythematous skin condition with skin barrier dysfunction, driven largely by filaggrin (FLG) deficiency; however, direct FLG-targeting therapeutics remains lacking. To identify novel natural products capable of enhancing FLG expression, we screened an in-house natural prod...

Chun-Zheng Wang, Ke Tang, Ying Guo · 0 citations

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