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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Chun-Yuan Gan

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Review Oct 2026

Nucleoside antitumor drugs: From molecular mechanisms and adaptive resistance to clinical translation.

Nucleoside-based anticancer drugs are still needed to treat solid tumours and blood cancers, but due to systemic toxicity and the emergence of resistance, they have performed poorly in clinical practice. These agents inhibit deoxyribonucleic acid (DNA) synthesis, disrupt ribonucleic acid (RNA) metabolism, or deplete nu...

Chun-Yuan Gan, Jin-Hu Xiang, Yao-Hua Liu et al. · 0 citations
Sep 2026

Click-crosslinked arginine-based nanoplatform for co-delivery of camptothecin and siSTAT3 for metastatic breast cancer therapy.

Metastatic breast cancer remains a major therapeutic challenge due to the limited efficacy of current treatments against both primary tumors and distant metastases. Here, we developed an arginine-based click-crosslinked nanoplatform for the co-delivery of camptothecin (CPT) and STAT3 siRNA (siSTAT3). The nanoplatform w...

Su-Bin Xiong, Jin-Hu Xiang, Xiao He et al. · 0 citations
Aug 2026

Cascade-responsive biomimetic nanoparticles remodel tumor metabolism and potentiate ferroptosis for synergistic therapy of aggressive breast cancer.

In vitro and in vivo evaluations confirm that R-A/G@Z effectively suppresses aggressive breast tumors while maintaining a good safety profile, offering a promising strategy for intelligent metabolic-chemodynamic cancer nanomedicine.

Nian-Ting Xiao, Xiao He, Da-Xiu Li et al. · 0 citations

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