Author

Chun-Yu Yu

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Open access Sep 2026

MED24 deficiency promotes R-loop accumulation and sensitizes to SN-38 in triple-negative breast cancer

Findings establish MED24 as a R-loop regulator that enhances SN-38 sensitivity, thereby revealing a previously uncharacterized biological function for MED24 and suggesting a potential therapeutic strategy for TNBC.

Tao Shen, Xin-Hua Liu, Pei Huang et al. · Cell Death & Disease · 0 citations