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Author

Chun-Yan Mu

2 papers indexed here

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Open access Sep 2026

Mechanistic Study on HSP90B1 Regulation of ClC-7 Ubiquitination to Restore Lysosomal Function in the Protection Proffered by DGMI Against Fluoride-Induced Cognitive Dysfunction.

BACKGROUND Fluorosis can induce cognitive dysfunction. The cognitive impairment caused by fluorosis is closely related to endoplasmic reticulum stress (ERS) and abnormal lysosomal acidification. However, the specific molecular mechanism is not known, and effective intervention strategies are lacking. Diterpene ginkgoli...

Rui Chen, Peng Xie, Xin-Rui Fan et al. · 0 citations
Open access Sep 2026

Hepatic Usp2 orchestrates de novo lipogenesis through G3bp2 stabilization and β-catenin activation

The escalating global burden of metabolic diseases including obesity, type 2 diabetes, and metabolic dysfunction-associated fatty liver disease (MAFLD)-highlights an urgent need to identify new therapeutic targets. Although elevated hepatic de novo lipogenesis (DNL) is a hallmark of metabolic dysfunction, targeting i...

Wei Wang, Hui Wang, Yi-Han Liu et al. · 0 citations

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