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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chun-Tong Li

h-index 6 View on Semantic Scholar

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Aug 2026

Activity-Based Ubiquitin-α-amidomethyl Acrylate Probe for Profiling of Ubiquitinating Enzymes and Deubiquitinases.

Activity-based ubiquitin probes have emerged as powerful tools for dissecting protein ubiquitination. In this work, we discovered that an α-amidomethyl-substituted acrylate electrophile exhibits markedly enhanced reactivity. Based on this finding, we designed and synthesized a new activity-based probe, ubiquitin-α-amid...

Lu-Yu Shi, Xu Li, Ying-Yue Zhang et al. · 0 citations

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