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Chun-Ni Feng

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Aug 2026

Remodeling lipid and mitochondrial homeostasis: a novel mechanism by which polydatin attenuates renal tubular senescence in chronic kidney disease.

PD rewires lipid metabolism, restores mitochondrial homeostasis, and activates the SIRT3/SOD2 axis to mitigate DNA damage and suppress tubular senescence, thereby halting CKD progression and position PD as a promising therapeutic candidate for senescence-associated kidney diseases.

Ting-Ting Wang, Hui Wang, Wenfeng Guo et al. · 0 citations

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