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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chun-Man Wu

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Open access Oct 2026

Detection of an EGFR L858R mutation following prolonged sequential ALK-TKI therapy in ALK-rearranged NSCLC: a case report

Anaplastic lymphoma kinase ( ALK )-rearranged non-small cell lung cancer (NSCLC) typically exhibits profound sensitivity to ALK tyrosine kinase inhibitors (TKIs). While sequential therapy with next-generation inhibitors has significantly improved long-term outcomes, acquired resistance remains an eventual challen...

Jun-Yue Deng, Juan Li, Yu-Hong Chen et al. · 0 citations

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