Author

Chun-Li Wei

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Open access Oct 2026

Leucine-derived isovaleric acid remodels the tumor microenvironment by degrading EIF3I.

Metabolic reprogramming and immune evasion are hallmarks of cancer. Although leucine is well known for regulating protein synthesis, its role in immunometabolic interactions within the tumor microenvironment (TME) remains unclear. In this study, we found that leucine supplementation significantly inhibited tumor growth...

Jia-Hui Xu, Zi-Ming Wang, Chun-Li Wei et al. · Pharmacological Research · 0 citations

Open access Aug 2026

Decoding DDX36 impact in lung cancer: expression, prognostics, and tumor progression

It is indicated that DDX36 contributes to malignant phenotypes and tumor growth in lung cancer, supporting its potential utility clinically as a biologically relevant diagnostic and prognostic biomarker, as well as a candidate therapeutic vulnerability.

Xia Jiang, Jingliang Cheng, Dong-Mei Xu et al. · Scientific Reports · 0 citations