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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Chun-Feng Qu

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2 papers indexed here

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Open access Oct 2026

Demoted CD4+ T-cell activity resulted from CTNNB1 mutations resists lenvatinib plus anti-PD1 in HCC

Hepatocellular carcinoma (HCC) patients frequently fail to respond to combined anti-PD1 immunotherapy, though pre-existing neoantigen-specific CD8⁺ T cells within tumor microenvironment are reinvigorated upon PD1 blockaded. Tumor-intrinsic mechanisms driving the therapeutic resistance in HCC remain unclear. Here, w...

Fei Zhao, Kun Chen, Yi-Qiao Deng et al. · 0 citations
Open access Sep 2026

Papillary Thyroid Carcinoma with Terminal Immune Exhaustion Phenotype Correlates with Increased Risk of Lymph Node Metastasis: An Exploratory Study Combining Flow Cytometry and TCGA

It was found that LNM-positive PTC exhibited a terminal immune exhaustion phenotype characterized by enrichment of PD-1hiTIM-3+ CD8+ T cells and regulatory T cells and regulatory T cells, alongside elevated pro-inflammatory cytokines.

Shiwei Wang, Huizhu Cai, Ruo-Chan Zhang et al. · 0 citations

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