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Author

Chun-Bo Chen

2 papers indexed here

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Open access Oct 2026

Intestinal 3-methylindole exacerbates sepsis-induced neuroinflammation through microglial NLRP3 inflammasome activation

A specific gut microbial pathway is identified and sepsis-induced expansion of Escherichia coli and its overproduction of the metabolite 3-methylindole are key aggravating factors, which contributes to a new mechanistic understanding of SAE pathogenesis.

Heng Fang, Si-Min Wu, Pei-Xian Huang et al. · 0 citations
Open access Sep 2026

Peripheral immune phenotyping identifies an immunosuppressed sepsis endotype with potential relevance for immune stratification

Although internally identified immune phenotypes in sepsis provide limited additional prognostic discrimination beyond established severity scores and routine laboratory indicators, they provide valuable insights into immune dysfunction and represent a potential framework for immune stratification.

Rong Luo, Yi-Xia Xie, Xiao-Fang Deng et al. · 0 citations

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