Objectives: This study employed an integrative strategy combining UPLC-MS-based phytochemical profiling, network pharmacology, and transcriptomics to systematically investigate the protective effects and potential mechanisms of LJF against ALD. Methods: An ALD model was established via chronic ethanol liquid diet feedi...
Lin Chen, Meng-Jie Zhang, Dong-Sheng Zhao et al.· Pharmaceuticals· 0 citations
Astragalus membranaceus (Fisch.) Bge. (Fabaceae), an important medicinal plant widely cultivated in China, is valued for its roots, which are extensively used in traditional medicine. In August 2023, a red core disease was observed in commercial A. membranaceus fields in Sanying Town, Guyuan City, Ningxia Hui Autonomou...
Zhao-Hui Zhu, Te Ma, Chuan-Zhi Kang et al.· Plant Disease· 0 citations
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive dysfunction. Docosahexaenoic acid (DHA), the most abundant ω-3 polyunsaturated fatty acid (PUFA) in the brain, is essential for neuronal structure and function. Although epidemiological studies generally associate higher DHA...
Xin-Hua Li, Yue Jin, Xiao-Yu Li et al.· Pharmacological Research· 0 citations
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