Development of a novel near-infrared fluorescent probe for nitroxyl imaging in acute kidney injury.
Nitroxyl (HNO), a short-lived reactive nitrogen species, participates in regulating cellular redox and nitrosative homeostasis, and its level fluctuations may reflect biochemical alterations associated with renal tubular injury during acute kidney injury (AKI). Therefore, the development of HNO fluorescent probes for A...