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Author

Chuankai Luan

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Review Open access Jul 2026

Exercise-induced anandamide–CB1R signaling and prefrontal–amygdala stress circuits in adolescent depression: a critical hypothesis-driven narrative review

Adolescent depression emerges during a developmental period characterized by ongoing maturation of corticolimbic and stress-regulatory systems. This narrative review critically evaluates a hypothesis that acute exercise-related endocannabinoid mobilization, particularly changes in circulating anandamide (AEA), may be l...

Yong-Xin Luan, Shupei Wang, Yutang Gao et al. · 0 citations
Review Open access Jul 2026

The lactate–HCAR1 axis in exercise psychiatry: a candidate mechanism linking bone marrow–brain immunity to inflammation-related depression

Exercise is increasingly acknowledged as an effective intervention for depression, yet the biological mechanisms underlying its antidepressant effects remain incompletely defined. Conventional models have emphasized brain-centered pathways, including BDNF signaling, monoaminergic modulation, hypothalamic-pituitary-adre...

Chuankai Luan, Chuanping Lei, Min Liu · 0 citations

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