Chuan-Jian Wu

Reprogramming the Myeloid-T Cell Ecosystem through Engineered Oncolytic Viruses for Durable Antitumor Immunity.

Oncolytic virotherapy (OVT) has emerged as a promising immunotherapeutic strategy that combines selective tumor destruction with systemic immune activation. However, durable clinical responses remain limited because current approaches largely focus on viral replication and oncolysis while overlooking the immune network...