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Chu-Han Wang

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Review Open access Oct 2026

Evolution-guided phage therapy for antimicrobial-resistant Acinetobacter baumannii: from resistance evolution and genomic plasticity to receptor-associated fitness trade-offs and clinical translation

Carbapenem-resistant Acinetobacter baumannii (CRAB) is sustained by environmental persistence, genomic plasticity, biofilm-associated tolerance, and rapid adaptation under antibiotic pressure. These features constrain conventional antibiotic regimens and make CRAB a relevant test case for evolution-guided antimicrobial...

Chu-Han Wang, Guo-Liang Zhang, Hong-Lan Huang · 0 citations

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