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Christopher R. D'Angelo

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Case report Open access Sep 2026

Disseminated Xanthogranuloma Harboring a GAB2::BRAF Fusion and MITF Pathogenic Variant Successfully Treated With Cobimetinib: A Rare Case Report.

Several activating mutations and gene fusions involving the mitogen-activated protein kinase (MAPK) pathway have appeared in the literature regarding histiocytic neoplasms. We identified a GAB2::BRAF fusion in a cutaneous lesion of a 36-year-old male who developed central diabetes insipidus and reddish-pink grouped pap...

Pauline C. Xu, Allison M. Cushman-Vokoun, Christopher R. D'Angelo et al. · 0 citations

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