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Christopher M. Barker

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Open access Sep 2026

Human iPSC-derived neurons identify West Nile virus neuropathogenesis signatures and reveal strain-dependent neuroattenuation

West Nile virus (WNV) is one of the leading causes of arthropod-transmitted encephalitis in the world, yet its effects on neurons, the principal target of WNV in the brain, remain poorly defined. Here we establish and use Ngn2-induced human iPSC-derived gluta-matergic neurons to define the neuronal response to WNV thro...

Alejandro Matía, Astrid Anaya, A. Akgul et al. · 0 citations

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