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Christopher J. Chang

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Jul 2026

Copper Shapes T Cell Metabolism and Epigenetics to Drive Pathogenic Th17 Cell Function in Autoimmunity 2259915

Pathogenic T helper 17 (pTh17) cells are a subset of CD4+ T cells driving autoimmune diseases including multiple sclerosis (MS). To identify transporters controlling pTh17 cells, we conducted an in vivo shRNA-based forward genetic screen using the experimental autoimmune encephalomyelitis (EAE) model of MS...

Lucile Noyer, Liwei Wang, Miki Jishage et al. · 0 citations

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