Christopher J. A. Cowie

103 A Medulloblastoma brain slice culture radiotherapy platform to dually assess therapeutic efficacy and toxic

Medulloblastoma is the most common malignant childhood brain tumour. Radiotherapy (RT) forms a key treatment pillar but is associated with significant late effects. Ex vivo brain slice cultures present a translational model that overcomes limitations of existing in vitro and in vivo alternatives. Slice cultures p...