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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Christopher H. Gibbons

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Open access Aug 2026

Cutaneous Alpha-Synuclein Deposition Informs Autonomic Function in Individuals with Early-Stage Multiple System Atrophy

Cutaneous phosphorylated alpha-synuclein deposition increased over time and correlated with objective orthostatic hypotension and autonomic symptom burden in early synucleinopathy, and may serve as a minimally invasive tool to support diagnosis, monitor progression, and stratify clinical trial participants.

P. Trujillo, Leah G. Mann, B. Bellaire et al. · 1 citation
Review Open access Aug 2026

Clinical utility of skin biopsy detection of phosphorylated alpha-synuclein in an outpatient practice

Introduction The neurodegenerative disorders characterized by deposition of phosphorylated alpha-synuclein (P-SYN) include Parkinson’s disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB). Diagnosis of synucleinopathies in clinical practice has been enhanced by recent updates to diagnostic gu...

T. Levine, R. Freeman, N. Murray et al. · 0 citations
Open access Jul 2026

Prospective Validation of the Movement Disorder Society Prodromal Multiple System Atrophy Criteria in Pure Autonomic Failure

The PP-MSA criteria demonstrate high sensitivity but limited specificity in patients with PAF and a stricter olfactory threshold improves diagnostic performance and may enhance cohort enrichment for clinical trials.

Patricio Millar Vernetti, J. Palma, I. Biaggioni et al. · 1 citation

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