Christopher A. Waudby

Solution structure, dynamics and fragment binding of unbound MERS-CoV nsp10

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) poses a significant public health threat, with a fatality rate of 37% and no approved therapeutics (World Health Organization, 2026). Non-structural protein 10 (nsp10) is an essential cofactor that activates both the nsp14 3’-5’ exoribonuclease (ExoN) activity req...