Author

Christopher A. Jin

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Open access Sep 2026

A positively selected microRNA controls a reversible aging program in striated muscle

It is shown that antisense oligonucleotide-mediated inhibition of miR-128-3p restores muscle mass and function in aged mice, improves cardiac function while limiting adverse remodeling following myocardial infarction, and ameliorates skeletal and cardiac muscle pathology in mouse and pig models of Duchenne muscular dys...

Melissa A. Boldridge, Lei Xu, Xiao-Yin Wang et al. · bioRxiv · 0 citations

Open access Aug 2026

Temporal multi-omic analysis uncovers sex-biased molecular programs underlying skeletal muscle adaptation to endurance training.

It is indicated that sex-specific skeletal muscle exercise adaptations are particularly evident at the PTM level in rats, and future avenues for precision exercise health and medicine are identified.

Gina M. Many, Christopher A. Jin, N. Day et al. · Cell Reports · 0 citations