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Author

Christoph Zrenner

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Open access Oct 2026

Excitation-Inhibition Balance and Fronto-Limbic Connectivity Distinguish TMS Treatment Outcomes in Refractory Depression.

BACKGROUND Intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) is effective for treatment-resistant depression, but outcomes remain variable. The neurophysiological mechanisms underlying response remain poorly understood, limiting precision neuromodulation. METHODS We...

D. Momi, Zheng Wang, M. P. Oveisi et al. · 0 citations
Open access Sep 2026

Spacing theta-burst stimulation enhances synaptic potentiation in the vulnerable prefrontal cortex

Neuromodulation with intermittent theta-burst stimulation (iTBS) is a clinical treatment for major depression. One postulated mechanism of iTBS is to strengthen the synaptic connections which activate the prefrontal cortex to regulate mood. With ex vivo electrical stimulation and neuronal calcium imaging, we demonstrat...

Angela Zolis, Angel Hsin-Yun Hsieh, Sridevi Venkatesan et al. · 0 citations

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