Open access
Oct 2026
Junctional plakoglobin regulates intestinal epithelial cell proliferation via MAPK/ERK signaling
Junctional plakoglobin (JUP) is a desmosomal protein essential for epithelial tissue integrity and epithelial-immune cell crosstalk. Although JUP has been implicated in inflammatory processes, its role in intestinal epithelial repair remains unclear. In vitro, loss of JUP in Caco-2 monolayers and non-transformed intest...
Marius Hörner, Natalie Burkard, Friedrich Forchel et al.
· Cell Communication and Signa... · 0 citations