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Author

Christine Herzog

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Open access Aug 2026

Structural origins of species-specific differences in TRPV2 activation

Transient receptor potential vanilloid 2 (TRPV2) is a broadly expressed ion channel implicated in diverse physiological and pathological processes. Despite strong conservation, human TRPV2 (hTRPV2) displays markedly reduced sensitivity to stimuli such as 2-aminoethoxydiphenyl borate (2-APB) and heat compared to rodent...

Tabea C. Fricke, R. Pumroy, Julia A. Rocereta et al. · 0 citations

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