Author

Christian A. Olsen

2 papers indexed here

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Open access Oct 2026

Immobilized Thiol Catalysts for Native Chemical Ligation in Flow

Native chemical ligation (NCL) is a well-established research tool used to access long and complex peptides that cannot be efficiently synthesized by other means such as linear solid-phase peptide synthesis (SPPS). However, its broader application beyond the research laboratory scale has been limited by low-volume yi...

P. H. G. Egelund, Jonathan Pfeuffer-Rooschüz, Sandip Jadhav et al. · JACS Au · 0 citations

Review Sep 2026

Investigation of the classical histone deacetylases and sirtuins using peptide technologies.

Histone deacetylase (HDAC) enzymes are hydrolases that remove acyl-based modifications from the side chains of lysine residues in our proteome. Originally named after their first identified substrates, the acetylated lysine residues in histone proteins, it has now become evident that individual isozymes of the HDAC cla...

Joseph M. Rogers, Christian A. Olsen · Cell Chemical Biology · 0 citations