Hypoxic microenvironments arise when local oxygen supply fails to meet cellular demand and exert an influence on the progression of cancer, ischemic heart and brain injury, chronic inflammatory disorders, and other diseases. Conventional approaches, including oxygen delivery systems, small-molecule redox drugs, and nat...
Yu-Han Yang, Yun Sun, Xing Sun et al.· Advances in Materials· 0 citations
A nitric oxide-driven nanomotor for reactive oxygen species (ROS)-responsive TH delivery (PMA@TH), enabling precise TH delivery to inflammatory lung tissues and demonstrating superior therapeutic outcomes in ALI models is demonstrated, offering a promising nanomedicine for clinical translation.