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Author

Chong Chen

2 papers indexed here

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Sep 2026

Targeting ClpP Rewires the Metabolic-Immune Axis in Acute Myeloid Leukemia.

Acute myeloid leukemia (AML) critically depends on oxidative phosphorylation (OXPHOS). Mitochondrial targeted therapies are advancing into clinical trials, but metabolic vulnerabilities have been primarily explored from a tumor-intrinsic perspective. Leukemic cells can actively reshape an immunosuppressive tumor microe...

Xin-Rong Xiang, Bao-Zhu Luo, Lei Zhao et al. · 0 citations
Review Open access Oct 2026

Mosaic Loss of the Y Chromosome: Mechanisms and Diseases.

Mosaic loss of the Y chromosome (mLOY) is a male‑specific somatic loss of the Y chromosome that is predominantly observed in peripheral blood leukocytes, but can also be found in other tissue types. It represents one of the most common male-specific somatic mutations, particularly prevalent in aging individuals. Accumu...

Qi Zhang, Jiang Yu, X. Zhai et al. · 0 citations

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