Structural basis of condensate formation of VAPB protein
Vesicle-associated membrane protein-associated protein B (VAPB) is an endoplasmic reticulum protein implicated in amyotrophic lateral sclerosis (ALS) through its P56S mutation. Although pathological function loss and condensate formation of the VAPB P56S mutant are crucial for disease progression, the underlying mole...
K. Furuita, Mayu Enomoto-Kusano, Wataru Togawa et al.
· Scientific Reports · 2 citations