BHLHE40 Orchestrates ILC3 and RORγt+ APC-Mediated Barrier Immunity 2309149
A central feature of the intestinal immune system is its ability to protect against pathogens while maintaining tolerance to commensal microbiota. Group 3 innate lymphoid cells (ILC3s), which express the transcription factor RORγt, produce effector cytokines such as IL-22 that are essential for epithelial repair...