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Author

Ching-Seng Ang

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Open access Sep 2026

Cell cycle dependent regulation of mRNA export in response to replication stress

A physical checkpoint at nuclear speckles is uncovered that regulates mRNA export during DNA replication in S-phase of the cell cycle and serves to protect the cell from major sources of genome instability by ensuring that R-loop associated mature mRNA is not exported to the cytoplasm.

Tobias D. Williams, Kirstyn T. Carey, W. Hamilton et al. · 0 citations

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