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Author

Chih-Hsiang Chang

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Review Open access Jan 2026

Diagnostic accuracy of the blood urea-to-creatinine ratio for differentiating AKI etiologies and dialysis prediction in adults: A systematic review and meta-analysis

Highlights • First meta-analysis of UCR diagnostic accuracy in AKI.• 9 studies (10 cohorts), 16,412 patients analyzed.• High UCR for pre-renal AKI: AUC = 0.69, modest sensitivity, low specificity.• High UCR for non-dialysis AKI: AUC = 0.63, limited discrimination.• Findings support cautious use given heterogeneity and...

Jia-Jin Chen, Tao-Han Lee, Yen-Ta Huang et al. · 0 citations
Open access Aug 2026

The benefit of LDL-C levels below 55 mg/dL in ESKD patients under statin treatment: A target trial emulation study.

BACKGROUND AND AIMS Achieving optimal low-density lipoprotein cholesterol (LDL-C) levels through statin therapy is a cornerstone of cardiovascular disease (CVD) prevention. However, its benefit in end-stage kidney disease (ESKD) remains uncertain, largely because two major randomized controlled trials-4D Study and AURO...

C. Yen, Pei-Chun Fan, Jia-Jin Chen et al. · 0 citations

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