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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Chih-Fang Liu

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Open access Aug 2026

Real-world implementation and evaluation of a pharmacogenomic clinical decision support system for allopurinol and HLA-B*58:01

Allopurinol-induced severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are strongly associated with the HLA-B*58:01 allele. Despite guidelines recommending genotyping prior to initiation, clinical implementation remains suboptimal. This s...

Kuan-Hsuan Chen, S. Goh, Chia-Lin Chou et al. · 0 citations

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