Open access
Oct 2026
Carbapenemase-producing
Enterobacterales
(CPE) are a critical global health threat with limited treatment options. Lactobacilli have been reported to exhibit antimicrobial activity against CPE, but whether this activity, together with key probiotic characteristics, is preserved after antibiotic-resistance induc...
Shao-Chuan Chen, Chi-Chung Chen, Chih-Cheng Lai et al.
· Frontiers in Microbiology · 0 citations
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Open access
Oct 2026
Chronic obstructive pulmonary disease (COPD) and type 2 diabetes (T2D) frequently coexist, sharing inflammatory and metabolic pathways. Tirzepatide (TZP), a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, has demonstrated metabolic and anti-inflammatory effects. Howev...
Wan-Hsuan Hsu, Yang-En Chan, Jheng-Yen Wu et al.
· Frontiers in Pharmacology · 0 citations
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Open access
Sep 2026
Background Whether pre-existing glucose-lowering therapy influences outcomes after sepsis remains uncertain. We compared clinical outcomes among patients with type 2 diabetes (T2D) who developed sepsis according to prior GLP-1 receptor agonists (GLP-1RAs) or SGLT2 inhibitors (SGLT2is) use. Methods We conducted a retros...
Hao-Hsun Liu, Sheng-Chi Huang, Jheng-Yen Wu et al.
· Drug Design, Development and... · 0 citations
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Open access
Sep 2026
Background: Recovery after hip fragility fracture surgery is heterogeneous. Explainable machine learning (ML) may help identify factors associated with short-term recovery during inpatient rehabilitation. Methods: This retrospective exploratory cohort included 88 patients who underwent surgery at our institution or two...
Chien-Hung Chen, Chin-Kai Huang, Chih-Cheng Lai et al.
· Diagnostics · 0 citations
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Aug 2026
BACKGROUND
Chronic obstructive pulmonary disease (COPD) is frequently complicated by acute respiratory failure, pneumonia, exacerbations, and premature mortality, particularly in patients with comorbid type 2 diabetes (T2D). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) possess anti-inflammatory and metabolic pr...
Kuang-Ming Liao, Ya-Wen Tsai, K. Kostikas et al.
· QJM : monthly journal of the... · 0 citations
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Aug 2026
In patients with CKD and type 2 diabetes mellitus, use of GLP-1RA is associated with lower risks of sepsis, all-cause mortality, pneumonia, urinary tract infection, and COVID-19 compared with DPP-4i, while the risk of septic shock was similar between groups.
Yu-Yang Tseng, Hsien-Yi Wang, Jui-Yi Chen et al.
· Nephrology, Dialysis and Tra... · 0 citations
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Aug 2026
In patients with COPD and T2DM, GLP-1RAs were associated with significantly lower risks of sepsis and all-cause mortality compared with SGLT2is.
K. Kuo, Chao-Hsien Chen, Tingjia Wu et al.
· Expert Review of Respiratory... · 0 citations
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