Open access
Sep 2026
Association between FNDC5 Deficiency and Compromised Mitochondrial Integrity and Biogenesis in Kidney Disease
Background Mitochondrial dysfunction is a hallmark of acute and chronic kidney diseases. This study investigates the expression landscape and potential association of FNDC5 with renal injury. Methods We integrated human scRNA-seq, mouse spatial transcriptomics (ischemia-reperfusion injury model), in vitro high-glucose...
Chien-Wei Huang, Chia-Jung Li, Junne-Ming Sung et al.
· International Journal of Med... · 0 citations