Open access
Aug 2026
Molecular heterogeneity and clonal origin of CCR8+ effector regulatory T cells in human cancer
CD4+CD25+FOXP3+ regulatory T cells (Treg) are highly activated in tumors and promote disease progression. Specific, universal targeting of these effector Treg cells is limited by the lack of a conserved signature across human cancers and information on their origin. Here we combine analysis of single-cell RNA-sequencin...
J. Swatler, S. Puccio, Emanuele Voulaz et al.
· Nature Communications · 0 citations