Open access
Oct 2026
Phosphoglycerate kinase 1 cooperates with the AP2 complex to promote endocytosis.
Adaptor proteins play a critical role in intracellular protein transport by binding to cargoes and facilitating their sorting into vesicles. The adaptor protein 2 (AP2) complex specifically recognizes sorting motifs on cargo proteins such as epidermal growth factor receptor (EGFR) and transferrin receptor (TfR) for pro...
Shao-Ling Chu, Yu-Tzu Chang, Che-Yu Hung et al.
· EMBO Reports · 0 citations