Author

Chi Zhang

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#protein folding Open access Oct 2026

MCT4-Associated Lactate Export Defines Myeloid Metabolic Reprogramming during Head and Neck Cancer Progression

Head and neck squamous cell carcinoma (HNSCC) develops within a metabolically remodeled tumor microenvironment, yet how metabolic programs evolve across specific cell populations during tumor progression remains poorly understood. We integrated single-cell RNA-sequencing data from five HNSCC cohorts comprising 645,351...

T. Tilton, Young Min Park, Hai-Qi Zhu et al. · bioRxiv · 0 citations

Open access Aug 2026

Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer

EmitGCL is developed, a deep-learning framework to predict metastasis and related biomarkers using cancer single-cell sequencing data, enabling and validating the discovery of occult metastases and breast cancer metastasis biomarkers.

Xiaoying Wang, Maoteng Duan, Anthony J. Snyder et al. · Nature Communications · 0 citations