Author

Chi-Lam Poon

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#artificial intelligence Preprint Oct 2026

Evaluating and improving AI agents for sequencing protocol understanding

LibStructBench is introduced, a document-grounded benchmark for reconstructing sequencing-library structures and molecular workflows and shows that frontier agents often produce approximately correct reconstructions but remain unreliable at exact reconstruction, particularly in molecular-state representation and workfl...

Chi-Lam Poon, Michael Goneos, Zezheng Song et al. · 0 citations

Jul 2026

KRAS G12D Blocks Erythroid Differentiation and Promotes Inflammatory Pathways at the Single Cell Level in Myeloid Malignancies 2251571

Genotyping of Transcriptomes is used to elucidate specific KRASG12D-driven pathways in preleukemic Clonal Hematopoiesis and 3 Acute Myeloid Leukemia patient samples and identify a novel quiescent CD83+ KRASG12D progenitor population in AML and demonstrate the therapeutic potential of MRTX1133 in vivo.

Leah Kravets, Ritesh Agarwal, Srinivas Aluri et al. · Journal of Immunology · 0 citations