Review
Open access
Aug 2026
Integrin α4β7: Pathogenic Roles in Metabolic and Inflammatory Diseases and Translational Therapeutics
Abstract Integrin α4β7 is a key adhesion receptor that mediates lymphocyte homing to the intestinal mucosa through interactions with MAdCAM-1, VCAM-1, and fibronectin, thereby playing a central role in gut immune surveillance and mucosal immunity. Emerging evidence has expanded its functional scope beyond intestinal ho...
Yue Chen, Yong Chen, Zhi-Yuan Zhang et al.
· Journal of Inflammation Rese... · 0 citations