Open access
Jul 2026
Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma
Long-read sequencing is employed to generate a high-resolution, isoform-level transcriptomic atlas from a cohort of 14 NPC tumor samples and four immortalized nasopharyngeal epithelial cell lines, and a new class of noncanonical neoantigens with significant potential for developing personalized cancer vaccines for NPC are identified.
Yi Shuai, Hualiang Yao, Bo Wang et al.
· Genome Research · 0 citations