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Chenxu Yan

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#protein folding Sep 2026

Discriminating Monomers and Fibrils of Amyloid‐ β 1–42 With Site‐Ordered Peptide‐QMFluors

ABSTRACT The detection of soluble amyloid‐ β (A β ), the most neurotoxic species in early Alzheimer's disease (AD), remains a major analytical challenge. Conventional probes are designed to target the β ‐sheet structures of mature fibrils and are thus blind to these transient, nonfibrillar species. Here, we introduce “...

Ruilong Dai, Jianfeng Dai, Chenxu Yan et al. · 0 citations
#protein folding Sep 2026

Discriminating Monomers and Fibrils of Amyloid-β1-42 With Site-Ordered Peptide-QMFluors.

The detection of soluble amyloid-β (Aβ), the most neurotoxic species in early Alzheimer's disease (AD), remains a major analytical challenge. Conventional probes are designed to target the β-sheet structures of mature fibrils and are thus blind to these transient, nonfibrillar species. Here, we introduce "site-ordered...

Rui-Long Dai, Jian-Feng Dai, Chen-Xu Yan et al. · 0 citations

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