Fluorinated and Iodinated Bottlebrush Polymers as an Efficient Platform for Oxygen-Enriched and Heavy-Atom-Mediated Photodynamic Therapy
Photodynamic therapy (PDT) is a noninvasive, spatiotemporally selective modality that affords rapid healing with negligible scarring, but its clinical efficacy is severely limited by tumor hypoxia and aggregation-induced quenching of photosensitizers. Perfluorocarbons possess excellent oxygen dissolution and transpor...