Author

Cheng-Yu Liu

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Sep 2026

Mitochondria-Targeted Nanozyme Reprograms Dendritic-Cell Immunometabolism via Microenvironment-Responsive CO Release to Treat Periodontitis.

Inflammatory diseases are characterized by overactivated immune responses and a disrupted metabolic equilibrium, particularly in dendritic cells (DCs), where mitochondrial reactive oxygen species (mtROS) burst and metabolic reprogramming drives pathological maturation. While modulating immunometabolism is a promising t...

Shangyan Shan, Cheng-Yu Liu, Li-Na Ding et al. · Advanced Healthcare Material... · 0 citations

Aug 2026

A proton-gated gold nanocluster platform for disrupting biofilm bioenergetics and suppressing virulence in bacterial infections.

This strategy demonstrates that targeting intracellular energy vulnerabilities can achieve antibacterial, antibacterial, antibiofilm, and antivirulence effects against persistent infections.

Jia Liu, Xiaolin Sun, Jing Zhou et al. · Biomaterials · 0 citations