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Cheng Qian

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Review Open access Oct 2026

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

Colorectal cancer (CRC) remains a leading cause of cancer incidence and mortality worldwide and is increasingly characterized by two converging realities: a substantial global burden and a rising incidence of early‐onset CRC. This review synthesizes current advances in CRC epidemiology, risk factors, signaling biology,...

Kai-Rui Wan, Ke Tang, Ling-Long Wang et al. · 0 citations
Review Open access Aug 2026

Spatial transcriptomic and proteomic approaches for profiling prognostic cell communities in solid tumors.

This review discusses how spatial transcriptomics and proteomics enable extraction of spatial metrics including cell density, proximity, and community-level organization and highlights critical spatial features, including immune cell infiltration patterns and vascular niches that are strongly linked to patient outcomes...

Xia Lei, Xuan Cui, Y. Ni et al. · 0 citations
Review Open access Jul 2026

Advances in enhanced mesenchymal stem cell technologies: innovations and therapeutic applications

This review systematically summarizes recent advances in MSC-enhanced therapeutic strategies, and elaborates on their core molecular mechanisms as well as how these mechanisms modulate MSC survival, homing capacity and immunomodulatory efficacy.

Shanshan Zheng, Yukang Huang, Xianli Yang et al. · 0 citations

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