Colorectal cancer (CRC) remains a leading cause of cancer incidence and mortality worldwide and is increasingly characterized by two converging realities: a substantial global burden and a rising incidence of early‐onset CRC. This review synthesizes current advances in CRC epidemiology, risk factors, signaling biology,...
Kai-Rui Wan, Ke Tang, Ling-Long Wang et al.· MedComm· 0 citations
This review discusses how spatial transcriptomics and proteomics enable extraction of spatial metrics including cell density, proximity, and community-level organization and highlights critical spatial features, including immune cell infiltration patterns and vascular niches that are strongly linked to patient outcomes...
Xia Lei, Xuan Cui, Y. Ni et al.· Journal of Advanced Research· 0 citations
This review systematically summarizes recent advances in MSC-enhanced therapeutic strategies, and elaborates on their core molecular mechanisms as well as how these mechanisms modulate MSC survival, homing capacity and immunomodulatory efficacy.
Shanshan Zheng, Yukang Huang, Xianli Yang et al.· Frontiers in Cell and Develo...· 0 citations
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